Research Articles
Ecological Validity in Virtual Reality: Advancing Naturalistic Neuroscience for Research and Drug Development
This article explores the critical role of ecological validity in virtual reality (VR) paradigms for naturalistic neuroscience research.
From Lab to Clinic: The Evolution of Virtual Reality in Modern Neuroscience
This article traces the transformative journey of virtual reality (VR) in neuroscience, from its early exploratory applications to its current status as an indispensable tool for research and therapy.
Virtual Reality as a Tool for Modulating Hippocampal Function and Spatial Navigation: Mechanisms, Applications, and Clinical Translation
This article synthesizes current research on the use of virtual reality (VR) to investigate and modulate hippocampal-dependent spatial navigation and memory.
Beyond Pairwise Networks: How Higher-Order Topological Indicators Are Revolutionizing Task Decoding Performance
Moving beyond traditional pairwise functional connectivity models, this article explores the transformative potential of higher-order topological indicators for enhancing task decoding performance in neuroimaging and biomedicine.
Triple Network Signatures in Personality and Psychopathology: A Translational Framework for Biomarker Discovery and Drug Development
This article synthesizes current research on the Triple Network Model—comprising the Default Mode, Salience, and Executive Control Networks—as a transdiagnostic framework for understanding the neurobiological underpinnings of personality traits and...
Brain Fingerprinting: Unlocking Individual Identity Through Functional Connectivity
This article provides a comprehensive exploration of functional connectivity (FC) as a unique and reliable biomarker for individual identification, known as brain fingerprinting.
Beyond Pairwise: How Higher-Order Interactions Are Reshaping Network Science and Drug Discovery
This article explores the critical shift in complex systems analysis from traditional pairwise connectivity to the incorporation of higher-order interactions (HOIs).
Brain Signatures Decoded: A Comparative Analysis of Explanatory Power in Neuroscience Research
This article provides a comprehensive comparative analysis of brain signatures, exploring their growing explanatory power in linking neural activity and structure to cognitive functions and behavioral outcomes.
Beyond Single Studies: A Framework for Replicable Consensus Models in Biomedical Validation Cohorts
This article provides a comprehensive guide for researchers and drug development professionals on ensuring the replicability of consensus prediction models across diverse validation cohorts.
Signature Models vs. Theory-Based Models: A Comprehensive Guide for Drug Development
This article provides a systematic comparison of data-driven signature models and mechanism-driven theory-based models in biomedical research and drug development.